Current Affairs - Miscellaneous - Discussion

In the journal 'Cell' researchers authored that the discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing. i. The research was headed by Amit Choudhary of the Broad Institute, Harvard Medical School, and Brigham and Women's Hospital. These first small-molecule CRISPR-Cas9 inhibitors are much smaller than the previously discovered anti-CRISPR proteins.