Biochemistry - Glycolysis - Discussion

Discussion Forum : Glycolysis - Section 1 (Q.No. 1)
Glycolytic pathway regulation involves
allosteric stimulation by ADP
allosteric inhibition by ATP
feedback, or product, inhibition by ATP
all of the above
Answer: Option
No answer description is available. Let's discuss.
9 comments Page 1 of 1.

Name said:   1 decade ago
Where is glycolysis stimulated by ADP? Phosphofructokinase is stimulated by AMP but not ADP because the concentration of ADP is not as variable as AMP.

PARBLO said:   1 decade ago
All of the above because the glycolysis depends on these founding blocks to operate.

Justtryingtohelp said:   9 years ago
I think the keyword is "stimulate" usually ADP means low ATP concern so it will cause more ATP to produced. Hence stimulate Glycolysis for ATP production.

Otile said:   9 years ago
Phospho kinase 1 enzyme has about 4 active sites i.e active site for ATP, Citrate, AMP & Fructose 2-6 Bisphosphate site, Increase in Fructose 2-6 Bisphosphate (a very powerful stimulant of Phospho Kinase 1).

ATP & Citrate, signals Phospho Kinase 1 to Phosphorylate more Fructose 6 phosphate into Fructose 1-6 bisphosphate. In my opinion this is the Enzymatic Allosteric Regulation.

ESILESI GERISHOM said:   7 years ago
I agree ADP helps in stimulation of glycolysis as it results from phosphorylating the glucose compound.

Flori said:   7 years ago
What is mean by stimulant and allosteric?

Daka Daka said:   2 years ago
Give more details about it.

Avocado said:   1 year ago
Allosteric means not in the active site.

Lorrine said:   1 year ago
Agree, option D. All above is the correct answer.

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