Biochemistry - Glycolysis - Discussion

Discussion :: Glycolysis - Section 1 (Q.No.1)


Glycolytic pathway regulation involves

[A]. allosteric stimulation by ADP
[B]. allosteric inhibition by ATP
[C]. feedback, or product, inhibition by ATP
[D]. all of the above

Answer: Option D


No answer description available for this question.

Name said: (Oct 18, 2013)  
Where is glycolysis stimulated by ADP? Phosphofructokinase is stimulated by AMP but not ADP because the concentration of ADP is not as variable as AMP.

Parblo said: (Nov 9, 2013)  
All of the above because the glycolysis depends on these founding blocks to operate.

Justtryingtohelp said: (Jul 10, 2015)  
I think the keyword is "stimulate" usually ADP means low ATP concern so it will cause more ATP to produced. Hence stimulate Glycolysis for ATP production.

Otile said: (Sep 6, 2015)  
Phospho kinase 1 enzyme has about 4 active sites i.e active site for ATP, Citrate, AMP & Fructose 2-6 Bisphosphate site, Increase in Fructose 2-6 Bisphosphate (a very powerful stimulant of Phospho Kinase 1).

ATP & Citrate, signals Phospho Kinase 1 to Phosphorylate more Fructose 6 phosphate into Fructose 1-6 bisphosphate. In my opinion this is the Enzymatic Allosteric Regulation.

Esilesi Gerishom said: (Mar 15, 2017)  
I agree ADP helps in stimulation of glycolysis as it results from phosphorylating the glucose compound.

Flori said: (Aug 28, 2017)  
What is mean by stimulant and allosteric?

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