Biochemistry - Glycolysis - Discussion

Discussion Forum : Glycolysis - Section 1 (Q.No. 3)
3.
Why does the glycolytic pathway continue in the direction of glucose catabolism?
There are essentially three irreversible reactions that act as the driving force for the pathway
High levels of ATP keep the pathway going in a forward direction
The enzymes of glycolysis only function in one direction
Glycolysis occurs in either direction
Answer: Option
Explanation:
No answer description is available. Let's discuss.
Discussion:
6 comments Page 1 of 1.

Ayubu said:   1 decade ago
Although most of the reactions in glycolysis are reversible they markedly exergonic and therefore must be termed as irreversible.
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Aron said:   1 decade ago
What are three pathway are irreversible?
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Otile said:   9 years ago
The most important and very crucial steps in Glycolysis are Phosphorylation of Glucose upto the stage when Fructose 1-6 bisphosphate is formed and the irreversible step 1 i.e Glucose Phosphorylation that helps Glucose to remain in polar state not to exit the cell (Hexokinase & Glucokinase),

And Phosphorylation of Fructose 6 phosphate into Fructose 1-6 Bisphosphate (PhosphoFructoKinase 1) which is actually under regulation very close stimulation and inhibition of (ATP, Citrate) and AMP respectively and ofcose Fructose 2-6 bisphosphate (formed by PhosphoFructokinase 2) avery powerful stimulant of PFK 1, and and inhibitor of gluconeogenesis enables the cycle in one direction.
(1)

Abdyaw said:   6 years ago
Yes, Right @Otile.

Chanda said:   2 years ago
What is the first 3 steps of glycolysis?

Saleh said:   2 years ago
Only three steps of glycolysis is irreversible which is also a regulatory step.

The first step, last step and PFK1.

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