Discussion :: Glycolysis - Section 1 (Q.No.3)
|Ayubu said: (May 3, 2012)|
|Although most of the reactions in glycolysis are reversible they markedly exergonic and therefore must be termed as irreversible.|
|Aron said: (Dec 26, 2012)|
|What are three pathway are irreversible?|
|Otile said: (Sep 6, 2015)|
|The most important and very crucial steps in Glycolysis are Phosphorylation of Glucose upto the stage when Fructose 1-6 bisphosphate is formed and the irreversible step 1 i.e Glucose Phosphorylation that helps Glucose to remain in polar state not to exit the cell (Hexokinase & Glucokinase),
And Phosphorylation of Fructose 6 phosphate into Fructose 1-6 Bisphosphate (PhosphoFructoKinase 1) which is actually under regulation very close stimulation and inhibition of (ATP, Citrate) and AMP respectively and ofcose Fructose 2-6 bisphosphate (formed by PhosphoFructokinase 2) avery powerful stimulant of PFK 1, and and inhibitor of gluconeogenesis enables the cycle in one direction.
|Abdyaw said: (Oct 16, 2018)|
|Yes, Right @Otile.|
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