Biochemistry - Glycolysis - Discussion
Discussion Forum : Glycolysis - Section 1 (Q.No. 3)
3.
Why does the glycolytic pathway continue in the direction of glucose catabolism?
Discussion:
6 comments Page 1 of 1.
Saleh said:
2 years ago
Only three steps of glycolysis is irreversible which is also a regulatory step.
The first step, last step and PFK1.
The first step, last step and PFK1.
Chanda said:
2 years ago
What is the first 3 steps of glycolysis?
Abdyaw said:
6 years ago
Yes, Right @Otile.
Otile said:
9 years ago
The most important and very crucial steps in Glycolysis are Phosphorylation of Glucose upto the stage when Fructose 1-6 bisphosphate is formed and the irreversible step 1 i.e Glucose Phosphorylation that helps Glucose to remain in polar state not to exit the cell (Hexokinase & Glucokinase),
And Phosphorylation of Fructose 6 phosphate into Fructose 1-6 Bisphosphate (PhosphoFructoKinase 1) which is actually under regulation very close stimulation and inhibition of (ATP, Citrate) and AMP respectively and ofcose Fructose 2-6 bisphosphate (formed by PhosphoFructokinase 2) avery powerful stimulant of PFK 1, and and inhibitor of gluconeogenesis enables the cycle in one direction.
And Phosphorylation of Fructose 6 phosphate into Fructose 1-6 Bisphosphate (PhosphoFructoKinase 1) which is actually under regulation very close stimulation and inhibition of (ATP, Citrate) and AMP respectively and ofcose Fructose 2-6 bisphosphate (formed by PhosphoFructokinase 2) avery powerful stimulant of PFK 1, and and inhibitor of gluconeogenesis enables the cycle in one direction.
(1)
Aron said:
1 decade ago
What are three pathway are irreversible?
(1)
Ayubu said:
1 decade ago
Although most of the reactions in glycolysis are reversible they markedly exergonic and therefore must be termed as irreversible.
(1)
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