Biochemistry - Carbohydrate - Discussion
Discussion Forum : Carbohydrate - Section 1 (Q.No. 5)
5.
Which of the following compounds is responsible for coordinated regulation of glucose and glycogen metabolism?
Discussion:
15 comments Page 2 of 2.
Abdullahi ymas said:
9 years ago
Thanks @Fatemeh.
Abhilash. D said:
9 years ago
Yes, I am familiar only about fructose-6-phosphate and fructose-1, 6-biphosphate.
Fatemeh said:
1 decade ago
Nope it is indeed b, fructose 6 phosphate is converted into fructose 1, 6 bis phosphate via pfk1.
However, it can also get converted into fructose 2, 6 bisphosphate via pfk2. The product of this reaction is then regulated via hormones insulin and glucagon in which an increase in insulin increases f26bp which stimulates the conversion of f6p to f16bp despite the negative effect (inhibitory) of acetyl co-a accumulation.
Hope this helped!
However, it can also get converted into fructose 2, 6 bisphosphate via pfk2. The product of this reaction is then regulated via hormones insulin and glucagon in which an increase in insulin increases f26bp which stimulates the conversion of f6p to f16bp despite the negative effect (inhibitory) of acetyl co-a accumulation.
Hope this helped!
Awar said:
1 decade ago
Phosphoglucomutase catalyze conversion of G6p to G1p and require Glucose 1,6 diphosphate and Mg++, so isn't B, its D.
Benjamin said:
1 decade ago
I have never heard of fructose-2, 6-bisphosphate.
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