Biochemistry - Carbohydrate - Discussion
Discussion Forum : Carbohydrate - Section 1 (Q.No. 5)
5.
Which of the following compounds is responsible for coordinated regulation of glucose and glycogen metabolism?
Discussion:
15 comments Page 1 of 2.
Fatemeh said:
1 decade ago
Nope it is indeed b, fructose 6 phosphate is converted into fructose 1, 6 bis phosphate via pfk1.
However, it can also get converted into fructose 2, 6 bisphosphate via pfk2. The product of this reaction is then regulated via hormones insulin and glucagon in which an increase in insulin increases f26bp which stimulates the conversion of f6p to f16bp despite the negative effect (inhibitory) of acetyl co-a accumulation.
Hope this helped!
However, it can also get converted into fructose 2, 6 bisphosphate via pfk2. The product of this reaction is then regulated via hormones insulin and glucagon in which an increase in insulin increases f26bp which stimulates the conversion of f6p to f16bp despite the negative effect (inhibitory) of acetyl co-a accumulation.
Hope this helped!
Fadel.A said:
7 years ago
Yes, Fructose-2, 6-Bisphosphate activate PFK-1 when insulin levels are high but I don't think that it is implicated in glycogen metabolism.
Awar said:
1 decade ago
Phosphoglucomutase catalyze conversion of G6p to G1p and require Glucose 1,6 diphosphate and Mg++, so isn't B, its D.
Nasir shah said:
5 years ago
The hormonal regulation of glycolysis and gluconeogenesis is mediated by fructose 2, 6-bisphosphate.
Abhilash. D said:
9 years ago
Yes, I am familiar only about fructose-6-phosphate and fructose-1, 6-biphosphate.
Hanan said:
8 years ago
Yes, fructose 2, 6 bisphosphate is an activator for glycolysis "pfk1".
Imran said:
2 months ago
Anyone, Please explain me in detail to understand this.
Benjamin said:
1 decade ago
I have never heard of fructose-2, 6-bisphosphate.
Apelle Diana said:
9 years ago
NAD is out the list because of its for sucrose.
Sara said:
8 years ago
I didn't get it, is the answer D or B and why?
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