Microbiology - Microorganisms and Disease - Discussion

Discussion Forum : Microorganisms and Disease - Section 1 (Q.No. 7)
Pseudomembraneous colitis is
precipitated by the use of certain antibiotics
caused by a gram-positive bacterium
caused by a spore-forming bacterium
all of the above
Answer: Option
No answer description is available. Let's discuss.
1 comments Page 1 of 1.

Safiya A said:   9 years ago
Clostridium difficile is a Gram-positive, spore-forming, anaerobic rod, manifests first as diarrhea and develops into "pseudomemranous colitis" also known as "antibiotic-associated colitis" because it follows antibiotic therapy to treat other bacterial infections.

Produce 2 toxins: Toxin A (an enterotoxin) causes fluid accumulation and damage the mucosa of the large bowel.

Toxin B: A cytotoxin that causes cytoskeltel changes and then kills mucosal cells.

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