Microbiology - Microorganisms and Disease - Discussion

Discussion Forum : Microorganisms and Disease - Section 1 (Q.No. 9)
9.
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause
ADP ribosylation of adenylate cyclase that stops production of cAMP
ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP
cleavage of rRNA that results in disruption of ribosome function
ADP ribosylation of guanylate cyclase that stimulates production of cGMP
Answer: Option
Explanation:
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Discussion:
1 comments Page 1 of 1.

Safiya A said:   9 years ago
Overproduce cAMP, which disrupts the fluid and electrolyte balance, causing hyper secretion of chloride and bicarbonate.

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