Microbiology - DNA Replication - Discussion

Discussion :: DNA Replication - Section 1 (Q.No.5)

5. 

Which of the following possesses both 5'-3' and 3'-5' exonuclease activity?

[A]. Kornberg enzyme
[B]. DNA polymerase III
[C]. Taq DNA polymerase
[D]. None of these

Answer: Option A

Explanation:

No answer description available for this question.

Lana said: (Oct 3, 2012)  
What is kornberg enzyme?

Mahi said: (Dec 2, 2012)  
Kornborg is an another name of DNA-Plimerase 1.

Nini said: (Apr 26, 2013)  
Kornberg enzyme is a DNA polymerase 1 which lacks 5'-3' exonuclease activity.

Rahul Aryan Raj said: (May 20, 2016)  
What is meant by exonucelease?

Nanoshe Taye said: (May 1, 2017)  
It is pol III which is involved in chromosome replication and it possesses 3'_5' and 5'_3'. And pol I is related to RNA primer removal.

So how that the answer be Kornberg enzyme (pol I)?

Neha Dar said: (Aug 13, 2017)  
What is the function of Kornberg enzyme?

Muskan said: (Aug 12, 2019)  
Pol I possesses four enzymatic activities:

A 5' --> 3' (forward) DNA-Dependent DNA polymerase activity, requiring a 3' primer site and a template strand.
A 3' --> '5' (reverse) exonuclease activity that mediates proofreading.
A 5' --> '3' (forward) exonuclease activity mediating nick translation during DNA repair.
A 5' --> '3' (forward) RNA-Dependent DNA polymerase activity.

Hassan said: (Aug 17, 2019)  
DNA pol 1.

5' to 3' exonuclease --> removal of primer.
5' to 3' polymerization ----> add nucleotides in place of primer(removed).
3' to 5'exonculease----> proofreading of this newly synthesized segment.

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