Discussion :: DNA Replication - Section 1 (Q.No.5)
Which of the following possesses both 5'-3' and 3'-5' exonuclease activity?
Answer: Option A
No answer description available for this question.
|Lana said: (Oct 3, 2012)|
|What is kornberg enzyme?|
|Mahi said: (Dec 2, 2012)|
|Kornborg is an another name of DNA-Plimerase 1.|
|Nini said: (Apr 26, 2013)|
|Kornberg enzyme is a DNA polymerase 1 which lacks 5'-3' exonuclease activity.|
|Rahul Aryan Raj said: (May 20, 2016)|
|What is meant by exonucelease?|
|Nanoshe Taye said: (May 1, 2017)|
|It is pol III which is involved in chromosome replication and it possesses 3'_5' and 5'_3'. And pol I is related to RNA primer removal.
So how that the answer be Kornberg enzyme (pol I)?
|Neha Dar said: (Aug 13, 2017)|
|What is the function of Kornberg enzyme?|
|Muskan said: (Aug 12, 2019)|
|Pol I possesses four enzymatic activities:
A 5' --> 3' (forward) DNA-Dependent DNA polymerase activity, requiring a 3' primer site and a template strand.
A 3' --> '5' (reverse) exonuclease activity that mediates proofreading.
A 5' --> '3' (forward) exonuclease activity mediating nick translation during DNA repair.
A 5' --> '3' (forward) RNA-Dependent DNA polymerase activity.
|Hassan said: (Aug 17, 2019)|
|DNA pol 1.
5' to 3' exonuclease --> removal of primer.
5' to 3' polymerization ----> add nucleotides in place of primer(removed).
3' to 5'exonculease----> proofreading of this newly synthesized segment.
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