Microbiology - Antimicrobial Chemotherapeutic Agents - Discussion

Discussion :: Antimicrobial Chemotherapeutic Agents - Section 1 (Q.No.7)

7. 

Novobiocin can be used against

[A]. gram +ve Staphylococci
[B]. gram -ve Meningococci & Gonococci
[C]. Haemophilus
[D]. all of these

Answer: Option D

Explanation:

No answer description available for this question.

Arun said: (Jul 20, 2014)  
Novobiocin is not used as therapeutic agent. Its used for diagnostic purpose only.

Emi said: (Jul 19, 2018)  
@Arun.

Novobiocin test is used to differentiate coagulase-negative staphylococci (CONS) and presumptively identify the isolate as Staphylococcus Saprophyticus (novobiocin resistant). It is usually performed on urine isolates (isolated from women of reproductive age groups) that are coagulase negative yet novobiocin. An antibiotic, C31H36N2O11, produced by the actinomycete Streptomyces Nivens, used primarily in research and to treat infections by gram-positive bacteria in certain animals.

Khushi said: (Jul 23, 2018)  
Novobiocin is an aminocoumarin antibiotic that was produced by the actinomycete Streptomyces niveus. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. Other antibiotics in the aminocoumarin class include coumermycin A1 and clorobiocin. Novobiocin is an aminocoumarin.

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