Microbiology - Antimicrobial Chemotherapeutic Agents - Discussion

Discussion :: Antimicrobial Chemotherapeutic Agents - Section 1 (Q.No.4)


Cycloserine inhibits

[A]. alanine racemase
[B]. D-alanyl - D-alanine synthetase
[C]. Both (a) and (b)
[D]. amidase

Answer: Option C


No answer description available for this question.

Khushi said: (Jul 23, 2018)  
Mechanism of action. Cycloserine works as an antibiotic by inhibiting cell-wall biosynthesis in bacteria. As a cyclic analogue of D-alanine, cycloserine acts against two crucial enzymes important in the cytosolic stages of peptidoglycan synthesis: alanine racemase (Alr) and D-alanine:D-alanine ligase (Ddl).

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