Microbiology - Antigen Antibody Reaction - Discussion

Discussion Forum : Antigen Antibody Reaction - Section 1 (Q.No. 5)
In which of the following case a large lattice is formed?
Antibody is in excess
Antigens and antibodies are in optimal proportion
Antigen is in excess
None of these
Answer: Option
No answer description is available. Let's discuss.
4 comments Page 1 of 1.

Ipsita said:   6 years ago
In equivalent zone, ab and ags are present in optimum conc, as abs are usually divalent and ags are multivalent the cab form bridge between 2 or more ags this linking result in a formation of the multimolecular lattice which makes the reaction visible to the eye.

In the case of post zone and prozone phenomenon, there is no proper linking occur and is less visible to the eye.

Okomba said:   7 years ago
In prozone phenomenon at the prozone the Antibodies are in excess and all antigens will bound there will be unbound antibodies, in equivalent zone antibodies and antigens will be at equilibrium and there will maximum bounding hence visible ppt. But in postzone the Antigens will be in excess hence there will unbound Antigens

Natthaya said:   1 decade ago
From the graph between Precipitation and increasing of amount Antigen.

Prozone : Ab>Ag you can see some agglutination.

Equivalent zone : because of the optimal proportion of Ab and Ag you can see maximum and largest lattice caused by ag-ab complex.

Postzone : It's hard to form lattice because low level of ab when compare with ag level.

Eku said:   1 decade ago
Because of the antigen antibody complex.

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