Microbiology - Antibody - Discussion

Discussion Forum : Antibody - Section 1 (Q.No. 3)
3.
Simulation of which of the following will lead to appearance of first antibody to appear following stimulation by an antigen?
IgM
IgA
IgE
IgG
Answer: Option
Explanation:
No answer description is available. Let's discuss.
Discussion:
2 comments Page 1 of 1.

Purbali said:   10 years ago
During B cell maturation, gene segments responsible for Ig production get rearranged to form functional genes. Antibody production solely depends on such VDJ rearrangements, and the CH gene segments are sequentially arranged as Cmu, Cdelta, Cgamma, Cepsilon, Calpha, thereby giving an initial IgM response for Cmu.

Suhaib said:   1 decade ago
How it could be IgM?

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