Microbiology - Antibody - Discussion

Discussion :: Antibody - Section 1 (Q.No.3)

3. 

Simulation of which of the following will lead to appearance of first antibody to appear following stimulation by an antigen?

[A]. IgM
[B]. IgA
[C]. IgE
[D]. IgG

Answer: Option A

Explanation:

No answer description available for this question.

Suhaib said: (Oct 29, 2014)  
How it could be IgM?

Purbali said: (Oct 6, 2015)  
During B cell maturation, gene segments responsible for Ig production get rearranged to form functional genes. Antibody production solely depends on such VDJ rearrangements, and the CH gene segments are sequentially arranged as Cmu, Cdelta, Cgamma, Cepsilon, Calpha, thereby giving an initial IgM response for Cmu.

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