Microbiology - Antibody - Discussion

Discussion Forum : Antibody - Section 1 (Q.No. 2)

Antibody

Self reactive antibodies are not found in significant concentration in normal serum because

it is impossible to generate a self-reactive antibody

self reactive B cells are killed by CD8 T cells

B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide

self reactive B cells switch to IgA which is all secreted and not present in serum

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