Biochemistry - TCA Cycle - Discussion

Discussion :: TCA Cycle - Section 1 (Q.No.2)


Why is the TCA cycle the central pathway of metabolism of the cell?

[A]. It occurs in the center of the cell
[B]. Its intermediates are commonly used by other metabolic reactions
[C]. All other metabolic pathways depend upon it
[D]. None of the above

Answer: Option B


No answer description available for this question.

Vin said: (Oct 3, 2014)  
There are certain reactions that can feed intermediates into the TCA cycle, these reactions are called Anaplerotic Reactions. As these intermediates are also part of other systems, it can suggest that process of TCA is flexible and will adapt to accommodate different conditions of the cell. e.g. when there is sufficient energy, TCA is less likely to take place.

Kevin Tony said: (Oct 19, 2014)  
The cycle provides intermediates like alpha-Ketoglutaric, citriate,isocitric and oxaloacetate. The oxaloacetate produced can then be channeled to gluconeogenesis pathway for formation of glucose.

Sulyman Ajao said: (Apr 10, 2017)  
It's because many body macromolecules (carbohydrate, lipid, and fatty acid) are produce or manufacture from the reaction that its intermediate pathway of above-mentioned compounds.

Nath said: (May 10, 2019)  
It's amphibolic.

There are other pathways that originate from the cylcle ie gluconeogenesis transamination heme synthesis and fatty acids synthesis.

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