Biochemistry - Glycolysis - Discussion

Discussion :: Glycolysis - Section 1 (Q.No.22)


Glucose from the breakdown of glycogen is obtained in

[A]. the liver by phosphorolysis
[B]. the muscles by phosphorolysis
[C]. the muscles by hydrolysis
[D]. both (a) and (b)

Answer: Option D


No answer description available for this question.

Chinmay Joshi said: (Jun 17, 2013)  
The enzyme glucose 6 phosphatase is not found in muscles so glucose is not likely to be the end product of glycogenolysis in muscles. Option A is correct.

Aswile Mwambembe said: (Jan 10, 2014)  
Muscles (skeletal muscles) tend to consume glucose rather than releasing it to the other tissue. They lack glucose-6-phosphate and Glucagon hormone which are essential for completing glycogenolysis to release energy.

Hedaia said: (Dec 11, 2014)  
Glucose can obtained by Glucose 6 phosphate in liver, which can not obtained by muscle because lack of Glucose 6 phosphate, it just gets Glucose 6 phosphate and continue to Glycolysis.

Abreham said: (Apr 16, 2015)  
Phosphorylation can lead to glucose only in liver.

Loui said: (Jun 29, 2015)  
The correct answer is B because muscle also needs glycogen.

Loui said: (Jun 29, 2015)  
Muscle which contains only hexokinase can use this enzyme to phosphorylate fructose producing F6P which is a direct glycolytic intermediate. In liver the glucokinase, is specific for glucose as a substrate, therefore it requires an alternative enzyme to phosphorylate fructose. Hepatic fructokinase can phosphorylate fructose on C-1 to produce fructose-1-phosphate (F1P).

Instead of F 1,6 biphosphate aldolase , the liver containing aldolase B that can use F1P as a substrate to generate dihdroxyacetone phosphate( DHAP) and glyceraldehyde. The DHAP is converted, by triose phosphate isomerase(TIM), to G3P while the glyceraldehyde is phosphorylated to G3P by triose kinase.

Ali said: (Apr 7, 2017)  
According to me, the correct answer is A.

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