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Biochemistry - Disease Associated with Immune System - Discussion

Discussion Forum : Disease Associated with Immune System - Section 1 (Q.No. 15)
Disease Associated with Immune System
15.
X-linked hyper IgM syndrome, resulting in high levels of serum IgM and low levels of serum IgG, is caused by a defect in CD40L expression. The specific immune event that would be prevented by a defective CD40L would be
activation of B cells by T-independent antigens
failure of B cells to provide co-stimulation for Th2 activation
failure of Th2 cells to provide co-stimulation for B cell isotype switching
failure of Th2 cells to provide co-stimulation for B cell proliferation
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