Biochemistry - Carbohydrate - Discussion

Discussion :: Carbohydrate - Section 1 (Q.No.4)


How many ATP equivalents per mole of glucose input are required for gluconeogenesis?

[A]. 2
[B]. 6
[C]. 8
[D]. 4

Answer: Option B


No answer description available for this question.

David said: (Dec 1, 2013)  
How does it happen?

Fatemeh said: (Jun 10, 2015)  
You know how glycolysis uses a total number of 2 atp and produces (2+2) 4 atps. So we know that gluconegenesis is the reverse of glycolysis and we know that the last step which produced 2 atp by converting pep to pyruvate is now divided into two steps of their own (pyruvate-> oaa and oaa-> pep).

Glycolysis is like this : 2 + 2 = 4.

Gluconeogenesis : 2 + (2 atp +2 gtp) = 6 which means we need a total of 6 to go ahead.

Side note:

Remember that we used two atp in glycolysis to begin with and now we are producing them with gluconeogenesis- we hydrolyze instead!

Mohammad said: (Feb 21, 2016)  
In glycolysis 2 atp and 2 NADH is produced which each NADH will convert to 3 atps during oxidative phosphorylation so 2 atps plus 6 atps is produced. So gluconeogenesis need 8 atps to produce glucose.

Mohammad said: (Feb 21, 2016)  
Glycolysis is an exergonic process it does not need energy to happens.

Apelle Diania said: (Dec 6, 2016)  
The number of carbon atom present in glucose is 6 which makes it an aldohexose.

Eve Waje said: (Dec 6, 2016)  
The number of carbon atom in glucose is 6.

Mollel E said: (Mar 5, 2019)  
For gluconeogenesis to occur there must be the presence of 4 ATP and 2 GTP in which for this case gtp is equivalent to ATP hence 6 ATP are required.

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