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Biochemistry - Carbohydrate - Discussion

Discussion Forum : Carbohydrate - Section 1 (Q.No. 36)
Carbohydrate
36.
Citric acid accumulation would
stimulate phosphofructokinase activity
stimulate fructose 1,6 diphosphatase activity
inhibit phosphofructokinase activity
both (b) and (c)
Answer: Option
Explanation:
No answer description is available. Let's discuss.
Discussion:
3 comments Page 1 of 1.
Maria Ashraf said:   3 years ago
Citrate directly inhibits the main regulators of glycolysis, phosphofructokinase-1 (PFK1) and phosphofructokinase-2 (PFK2) [2, 3], while it enhances gluconeogenesis by promoting fructose-1, 6-biphosphatase (FBPase).
Mohammed said:   7 years ago
How come? Please explain.
Angie said:   9 years ago
If it inhibits PFK-1 how would it stimulate F1, 6BP?
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