Biochemistry - ATP Synthesis and Fatty Acid Oxidation - Discussion

Discussion :: ATP Synthesis and Fatty Acid Oxidation - Section 1 (Q.No.5)


The oxidation of methanol (wood alcohol) in human retina tissue leads directly to the formation of

[A]. formaldehyde
[B]. sugars
[C]. CO2
[D]. none of these

Answer: Option A


No answer description available for this question.

Christine said: (Feb 16, 2017)  
Why it forms formaldehyde in human retina tissue? Doesn't formaldehyde hurt the retina tissue?

Zhander said: (Jun 18, 2019)  
Methanol is metabolized in exactly the same way as ethanol. It is an oxidation reaction from an "OH to an "OOH. Just like ethanol, the first step changes the alcohol to the aldehyde, and the second step changes the aldehyde to the carboxylic acid. From methanol though, formaldehyde and formic acid are produced instead of the harmless acetic acid (as in the case of ethanol). Both formaldehyde (formed by alcohol dehydrogenase) and formic acid (methanoic acid formed by alcohol dehydrogenase) are deadly, first attacking cells in the retina and then the cells of other vital organs. It is for this reason that methanol should never, ever be consumed.

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