Biochemistry - Amino Acid Metabolism - Discussion

Discussion :: Amino Acid Metabolism - Section 1 (Q.No.1)


Histidine is degraded to α-ketoglutarate and is described as a

[A]. gluco amino acid
[B]. glucogenic amino acid
[C]. ketogenic amino acid
[D]. keto-gluco amino acid

Answer: Option B


No answer description available for this question.

Namara Dave J said: (Oct 16, 2013)  
Ketoglutarate is an intermediate in the TCA cycle.

Jemimah Mansibang said: (Mar 8, 2014)  
Histidine is an essential and a glucogenic amino acid.

Avicenna said: (Mar 24, 2014)  
Histidine is deaminated to urocanic acid, which is converted to 4-imidazolone 5-propionate. Hydrolysis of the later gives N-formiminoglutamate (FIGlu, which donates its formimino group to tetrahydrofolate, leaving glutamate which is then converted to alpha-ketoglutarate. Alpha-ketoglutarate is an intermediate in the Kreb's Cycle. Any amino acid whose catabolism gives pyruvate or one of the intermediate of Citric Acid Cycle is glycogenic amino acid.

Khan Arabi said: (May 29, 2015)  
So it gives a glycogenic amino acid x-tics.

Nikki said: (Jan 13, 2016)  
Histidine give alpha-ketoglutarate which can be used to produce glucose through reverse steps of glycolysis with specific enzyme.

So it is a glycogenic amino acid.

Joaness said: (Mar 4, 2017)  
Histidine is a glucogenic amino acid since it is converted to an intermediate alpha-ketoglutarate which is an intermediate in glucose metabolism in TCA cycle.

Apra said: (May 22, 2018)  
Glucogenic amino acids are those amino acids which can be converted into glucose by gluconeogenesis.

Neydee said: (Mar 26, 2021)  
I agree histidine is glucogenic amino acid since it has the ability to release the intermediate (α ketoglutarate) that can be used in the glycolytic pathway in the mitochondria.

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