Biochemistry - Amino Acid Metabolism - Discussion

I agree histidine is glucogenic amino acid since it has the ability to release the intermediate (α ketoglutarate) that can be used in the glycolytic pathway in the mitochondria.

Glucogenic amino acids are those amino acids which can be converted into glucose by gluconeogenesis.

Histidine is a glucogenic amino acid since it is converted to an intermediate alpha-ketoglutarate which is an intermediate in glucose metabolism in TCA cycle.

Histidine give alpha-ketoglutarate which can be used to produce glucose through reverse steps of glycolysis with specific enzyme.

So it is a glycogenic amino acid.

So it gives a glycogenic amino acid x-tics.

Histidine is deaminated to urocanic acid, which is converted to 4-imidazolone 5-propionate. Hydrolysis of the later gives N-formiminoglutamate (FIGlu, which donates its formimino group to tetrahydrofolate, leaving glutamate which is then converted to alpha-ketoglutarate. Alpha-ketoglutarate is an intermediate in the Kreb's Cycle. Any amino acid whose catabolism gives pyruvate or one of the intermediate of Citric Acid Cycle is glycogenic amino acid.

Histidine is an essential and a glucogenic amino acid.

Ketoglutarate is an intermediate in the TCA cycle.